Recurrence risk after neural tube defects in a genetic counselling clinic.
نویسندگان
چکیده
The recurrence of isolated neural tube defects in a population of women from a genetic counselling clinic was found to be 3.4%. After one baby with a neural tube defect the recurrence was 2.3%. Of the 15 pregnancies of women who had two previous babies with neural tube defects, there were three further recurrences. These findings show that the Hungarian recurrence risk of isolated neural tube defects has not changed with a declining birth prevalence, and that the rate in genetic counselling clinic patients is the same as in a previous population based epidemiological study.
منابع مشابه
Neural tube defects in Gauteng, South Africa: recurrence risks and associated factors.
BACKGROUND After congenital heart disease, neural tube defects (NTDs) are the most common serious structural birth defects in human infants. OBJECTIVES To (i) determine the recurrence risks of NTDs in the population of Gauteng; (ii) investigate some of the risk factors shown to be important in the occurrence of NTDs in other populations; and (iii) determine their relative importance in the ae...
متن کاملNeural tube defects: A need for population-based prevention program
through spinal defect and histopathological fi ndings.[2] Majority of NTDs are isolated/non-syndromic and are not associated with other congenital malformations. However in about 10% of the cases, NTD can be a part of genetic syndrome hence may follow Mendelian inheritance. The syndromes associated with neural tube defects include Walker-Warburg syndrome, Jarcho-Levin syndrome, Robert syndrome ...
متن کاملRecurrence of neural tube defect in a group of at risk women: a 10 year study of Pregnavite Forte F.
It is now more than a decade since Smithells et all first reported an apparent reduction in the recurrence rate in women at risk for a neural tube defect (NTD) when they were supplemented with Pregnavite Forte F around the time of conception. A multicentre study2 and a further report by Smithells et aP support this observation. We summarise the findings of our own 10 year study, which adds to t...
متن کاملMeckel syndrome and the prenatal diagnosis of neural tube defects.
Two fetuses, terminated after prenatal diagnosis of aneural tube defect, had Meckel syndrome. There have now been three fetuses with this syndrome in a series of 35 terminated because of open lesions of the neural tube. It is suggested that such therapeutically aborted fetuses represent a highly selected group, among which a rare condition like Meckel syndrome will be concentrated. The need for...
متن کاملI-19: Risks of Multiple Pregnancy, Preterm
Advances in treating infertile couples by assisted reproductive technologies (ART) over more than three decades have greatly improved the chances of better outcomes. While twinning and higher order multiple birth rates are still high in most countries, lower rates have sometimes been achieved by single-embryo transfer. Multiple preg- Abstracts of the 12th Royan International Congress on Reprodu...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of medical genetics
دوره 21 6 شماره
صفحات -
تاریخ انتشار 1984